The UW College of Engineering features Dr. David Younger, a postdoc in the lab of NanoES faculty member Eric Klavins. Younger is the founder/CEO of A-Alpha Bio, a spinout focused on accelerating drug development by providing quantitative and high-throughput measurements of protein-protein interactions.
Dr. Shreyas Shah, a postdoc working with Karl Böhringer and Arka Majumdar on an integrated photonics project, has been awarded an Unfettered Research Grant award to the tune of $10,000 by the Mistletoe Research Foundation. The Mistletoe Research Foundation, founded in 2017, builds bridges between the academic, entrepreneurial, and civil communities to create a more human-centered and sustainable future through technology.
Hal Holmes, a doctoral candidate of Bioengineering working with NanoES Director Karl Böhringer, has been selected as one of 14 Schmidt Science Fellows in the inaugural year of this prestigious program initiated by Eric and Wendy Schmidt.
Please join the third Innovations in Imaging for Life Sciences Symposium at the University of Washington on June 20, 2018. The talks will focus on advances in imaging from atomic to tissue scales, including cryo-electron microscopy and volume scope imaging.
To register (no charge) please go here: https://catalyst.uw.edu/webq/survey/jkoll/353918
PrimeNano will give a talk on the method May 1st from 10:00 am – 11:30 am in MolES 215. They will then provide demos on the technique using our AFM Dimension Icon that afternoon and the next day.
Speaker Bio: Oskar Amster, M.S. (Sr. Dir. Marketing of PrimeNano, Inc)
Mr. Amster has a background in Physics and Materials engineering with a focus on microelectronics processing. He has 20 years experience working with analytical instruments and metrology tools. His background is in applications development, strategic marketing, and product development. He has extensive experience working in Atomic Force Microscopy, Stylus Profilers, and Optical Profiler instruments. Prior to joining PrimeNano, Inc, Oskar was at KLA-Tencor and also held positions at several start-ups as well as mature instrument companies. He holds an MS in Materials Engineering and BS in Physics from Cal Poly San Luis Obispo.
Body-on-a-Chip: an application of three-dimensional microstructuring techniques
Yoshikazu HIRAI
Department of Micro Engineering, Kyoto University, JAPAN
E-mail: hirai@me.kyoto-u.ac.jp
http://www.nms.me.kyoto-u.ac.jp/en/member/hirai/
NanoES 291
Abstract
This presentation introduces three-dimensional (3-D) microstructuring methods based on optical lithography and addresses one of their application for developing “Body-on-a-Chip.” In vitro cell-based assay with human cells is getting attention since the accuracy of preclinical predictions of drug responses should be improved to reducing costly failures in clinical trials. In order to generate reliable predictions, we have developed a micro-engineered biomimetic systems “Body-on-a-Chip,” to investigate the effects of drugs/metabolites on multi organs by assembling a closed-loop medium circulation system on one microfluidic device. For 3-D polymeric sensor/actuator device fabrication, an advanced 3-D lithography with the process optimization was applied to improve device performances. Our Body-on-a-Chip was successfully applied to evaluate the effect of an anti-cancer drug (doxorubicin) on cell survival of human heart and liver cells.
Biography
Yoshikazu Hirai received the B.S. and M.S. degrees from Ritsumeikan University, Japan, in 2002 and 2004, respectively, and the Ph.D. degree from Kyoto University, Japan, in 2007, all in mechanical engineering. He was a Post-doctoral Researcher with the Graduate School of Engineering, Kyoto University. In 2009, he joined the Advanced Biomedical Engineering Research Unit, Kyoto University. Since 2013, he has been an Assistant Professor with the Department of Micro Engineering, Kyoto University. Dr. Hirai was a recipient of the Outstanding Reviewer Award in 2016 (Journal of Micromechanics and Microengineering, IoP) and the Institute of Electrical Engineers of Japan (IEEJ) Distinguished Paper Award in 2017. His current research interests include (1) Fabrication and packaging technologies for MEMS, (2) Optical lithography for 3D microstructuring, (3) Atomic sensor device (e.g., CSAC: Chip Scale Atomic Clock, CSAM: Chip Scale Atomic Magnetometer), and (4) Microfluidic system/device for biomedical applications.
NanoES is one of 16 primary sites in the National Nanotechnology Coordinated Infrastructure (NNCI). Learn more about what NNCI is and their goals for nanotechnology in this promotional video.
The team behind A-Alpha Bio, including David Younger, a postdoc in the lab of Eric Klavins and A-Alpha Bio CEO, won the $15,000 grand prize at the 2018 Hollomon Health Innovation Challenge.
Controlling Light with Metasurfaces
Gleb M. Akselrod, CTO and Co-Founder, Holosense
Feb. 27, 3:30 PM, EEB 303
Metasurfaces are surfaces composed of sub-wavelength elements that offer an unprecedented way to manipulate light. In this talk I will first describe my work from Duke University on colloidal metasurfaces, which act as unique “paints” that can manipulate the appearance of objects at various spectral bands. Then I will describe how metasurfaces can be made dynamic, with one of the most exciting applications being spatial light modulation for imaging. The most exciting of these imaging applications is lidar for self-driving cars, which my company, Holosense, is currently developing.
Gleb M. Akselrod is the CTO and co-founder of Holosense, which is a venture-backed company in Seattle developing high-performance solid-state lidar based on metasurface technology. Previously he was the Director for Optical Technologies at Intellectual Ventures in Bellevue, WA, where he led a program on the commercialization of optical metamaterial and nanophotonic technologies. Before that he was a postdoctoral fellow in the Center for Metamaterials and Integrated Plasmonics at Duke University, where his work focused on plasmonic nanoantennas and metasurfaces. He completed his PhD in 2013 at MIT, where he studied the transport and coherence of excitons in nanostructured materials.
Interactions between light and matter lie at the heart of optical communication and information processing. Nanophotonic devices enhance light-matter interactions by confining photons to small mode volumes, enabling devices to operate at significantly lower energies. In the strong coupling regime these interactions are sufficiently large to generate a nonlinear response with a single photon, an essential component for quantum information processing applications. In this talk I will describe our effort to couple spin to light using nanophotonics. I will discuss an experimental demonstration of a quantum transistor, a fundamental building block for quantum computers and quantum networks, using a single electron spin that strongly interact with light through a nanophotonic cavity. This device enables the spin to switch a single photon, and a single photon to flip the spin. I will discuss how the nanophotonic transistor can realize high fidelity all-optical spin readout, as well as a single photon transistor where one control photon can switch many signal photons. Finally, I will describe our recent effort to extend our results into the telecommunication wavelengths, and to integrate multiple devices on a chip to assemble integrated quantum photonic circuits.
Please join the Electrical Engineering Department for the 2017-18 Research Colloquium Series on Tuesday mornings, featuring experts who discuss current issues in the electrical engineering field. Talks are open to both students and the public. Live streaming is available for most talks.